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Article in English | IMSEAR | ID: sea-64955

ABSTRACT

Intravesical bacillus Calmette-Guerin (BCG) is used in patients with urinary bladder carcinoma. Although it is generally well tolerated, granulomatous hepatitis is a rare but serious complication. We report a 42-year-old man and a 56-year-old man who developed granulomatous hepatitis following intravesical BCG. One of them was treated successfully with antitubercular therapy; the other died because of BCG sepsis and multi-organ failure.


Subject(s)
Administration, Intravesical , Adult , Antitubercular Agents/therapeutic use , BCG Vaccine/adverse effects , Biopsy, Needle , Carcinoma, Transitional Cell/drug therapy , Fatal Outcome , Humans , Liver/microbiology , Male , Middle Aged , Tuberculosis, Hepatic/drug therapy , Urinary Bladder Neoplasms/drug therapy
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